Formal Research Experience

2015	Graduate Thesis Research Program in Molecular and Cellular Biology, The University of Iowa College of Medicine Mentor: Frederick Domann, Ph.D.

2008 – 2009

Doris Duke Research Fellow Doris Duke Research Fellow Program, The University of Iowa Hospitals and Clinics Mentor: Raymond Hohl, M.D., Ph.D.

2007	Summer Medical Student Research Fellow Children’s Memorial Hospital, Northwestern University and Midwestern University Mentors: Lon Van Winkle, Ph.D. and Philip Iannaccone, M.D., Ph.D.

2005 – 2006

Research Assistant I Department of Pharmacology, The University of Iowa College of Medicine Mentor: Nancy Lill, Ph.D.

2003	Undergraduate Summer Research Fellow Pharmacology Undergraduate Research Program, The University of Iowa College of Medicine Mentor: Nancy Lill, Ph.D.

Honors, Awards and Fellowships

2017	Maternal Fetal Medicine Resident Award, University of Iowa MFM Division
2013	Outstanding Poster Award, University of Iowa Health Sciences Research Week
2012	Outstanding Poster Award, American Osteopathic Medical Association National Research Conference
2012	Student Research Fellowship, National Student Osteopathic Medical Association
2012	Seed Grant Recipient, American Medical Association Foundation
2011	TL-1 Linked Training Award (Full Graduate Stipend), Institute for Clinical and Translational Medicine
2010	Graduate Student Senate Travel Award, University of Iowa Graduate Student Senate
2010	Young Investigator’s Award, National Society for Free Radical Biology and Medicine
2008	Doris Duke Clinical Research Fellowship, University of Iowa
2008	Basic Science Award in Biochemistry, Midwestern University Class of 2010
2007	Summer Medical Student Research Fellowship, Midwestern University/CCOM
2004	Outstanding Poster Award, University of Iowa Biosciences Poster Competition
2004	Travel Award, American Society of Biochemistry and Molecular Biology Annual National Meeting
2003	Summer Undergraduate Research Fellowship, University of Iowa Department of Pharmacology

Professional Societies and Service Committees

2013 – Present	Grant Reviewer – American Medical Association Foundation Seed Grant Committee
2014 – Present	Member – American Congress of Obstetricians and Gynecologists
2015	Official Reviewer – Journal of Oxidative Medicine and Cellular Longevity
2015	Official Reviewer – PLoS ONE
2006 – 2013	Member – American Osteopathic Association
2009 – 2013	Member – Society for Free Radical Biology and Medicine

Service and Extracurricular

2012 – 2015	Volunteer patient examiner, Chicago Community Health Clinic
2009 – 2013	Volunteer patient examiner, Iowa City Free Medical Clinic
2008 – 2009	Volunteer patient guide, Iowa City Free Medical Clinic
2007 – 2008	President and founder, CCOM Research Club

---

Peer-Reviewed Publications

1. Place, T. L., Domann, F.E., Case, AJ. Limitations of Oxygen Delivery to Cells in Culture: An Underappreciated Problem in Basic and Translational Research. Free Radical Biology and Medicine. 113:311-322 (2017).
2. Place, T. L. & Mezhir, J. J. Minimally Invasive Approaches to Resection for Pancreatic Adenocarcinoma: An Evidence Based Literature Review. J Gastrointest Surg. 19(2):375-86 (2015)
3. Place, T. L. et al. A Novel Role for Prolyl-hydroxylase 3 in Epithelial-to-Mesenchymal Transition. PLoS ONE 8(12):e83021 (2013).
4. Place, T. L. & Domann, F.E. Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein. Hypoxia. I, 13-27 (2013).
5. Place, T. L. & Mezhir, J. J. Molecular Characterization of Desmoid Tumors: Decryption of the Enigma. Onkologie 35:641-642 (2012).
6. Place, T. L. et al. Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. PLoS ONE 6(1):e14617 (2011).
7. Visser Smit, G. D. Place, T. L. (co-first author) et al. Cbl controls EGFR fate by regulating early endosome fusion. Science Signaling. 2(102):ra86 (2009).
8. Cao, X. R, Place, T. L. et al. Nedd4 controls animal growth by regulating IGF-I signaling. Science Signaling 1:ra5 (2008).
9. Stern, K. A., Place, T. L. & Lill, N. L. EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate. Biochem J 410, 585-594 (2008).
10. Stern, K. A. Place, T. L. et al. Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation. Molecular and Cellular Biology 27,888-898 (2007).

Selected Oral Research Presentations

1. Trenton L. Place. A Novel Role for Prolyl-Hydroxylase 3 Gene Silencing in Epithelial to Mesenchymal-Like Transition. Biochemistry Departmental Seminar, 2012. Midwestern University. Invited Speaker.
2. Trenton L. Place, James J. Mezhir, Frederick Domann. Prolyl-hydroxylase 3 silencing correlates with epithelial to mesenchymal transition (EMT) in pancreatic ductal adenocarcinoma. American College of Surgeons Clinical Congress 2012. Chicago, IL. Oral Presentation.
3. Trenton L. Place, James J. Mezhir, Frederick Domann. HIF Prolyl-hydroxylase 3 Silencing Correlates With a Mesenchymal Transcriptional Program in Human Pancreatic Cancer Cells. CTSA National Meeting 2012, Mayo Clinic. Oral Presentation.
4. Trenton L. Place, James J. Mezhir, Frederick Domann. HlF Prolyl-hydroxylase 3 Silencing Correlates With a Mesenchymal Transcriptional Program in Human Pancreatic Cancer Cells. University of Iowa Jakobson Conference, 2012. Oral Presentation.

Selected Research Poster Presentations

1. Trenton L. Place and Frederick E. Domann. Actin Proline Hydroxylation: Discovery of a Novel Actin Post-Translational Modification and Implications for the Effects of Hypoxia on Tumor Metastasis. CTSA National Meeting 2013, Mayo Clinic. Poster Presentation
2. Trenton L. Place, James 1. Mezhir, Frederick Domann. HIF Prolyl-hydroxylase-3 plays a key role in Epithelial to Mesenchymal Transition. Osteopathic Medical Conference 2012, San Diego, CA. Poster
3. Trenton L. Place, Sujatha Venkataraman, Matthew P. Fitzgerald, Sabine Von’ink, Adam 1. Case, Melissa L.T. Teoh, and Frederick E. Domann. Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. FRBM Conference. Orlando, Fl. November 2010. Poster
4. Trenton Place, Dave Schmitz, Lenore Pitstick, AI Campione, Lon Van Winkle. Glutamate and C-myc: Interplay for the Growth and Maintenance of Pluirpotent Human Embryonic Stem Cells? Midwestern University Research Day, Poster Presentation, Midwestern University, May 2008. Poster
5. Nancy L. Lill, Gina D. Visser Smit, Trenton L. Place, and Kathryn A. Stern. The Cbl RING Finger Tail Regulates Sorting of Endosome Fusion. Keystone Symposia, Big Sky, Montana, January 12-17, 2008. Poster
6. Nancy Lill, Kathryn Stern, Gina Visser, Trenton Place. Cbl Regulates EGF Receptor Fate at Two Endocytic Trafficking Checkpoints. Experimental Biology, San Francisco, CA, April 1-5, 2006. Poster
7. Trenton Place, Gina Visser, Kathryn Stern, Nancy Lill. Cbl RF-tail Residues Control EGF-R Fate at Two Distinct Endocytic Trafficking Checkpoints. University of Iowa Research Week 2006, University of Iowa, March 29-30, 2006. Poster
8. Trenton Place, Kathryn Stem, Nancy Lill. Mapping the Site of Hrs Regulation by Cbl. University of Iowa Biosciences Undergraduate Poster Competition, University of Iowa, September 1, 2004. Poster
9. Trenton Place, Kathryn Stern, Nancy Lill. Mapping the Site of Hrs Regulation by Cbl. American Society for Biochemistry and Molecular Biology, Boston, MA, June 15, 2004. Poster
10. Kathryn Stern, Trenton Place, Gina Visser, Nancy Lill. Regulation of Hrs posttranslational modification by Cbl. American Society for Biochemistry and Molecular Biology, Boston, MA, June 14 2004. Poster